Effectiveness of ChAdOx1 nCoV-19 (COVISHIELD) vaccine against the delta variant of SARS-CoV-2 in India

0
398
Novel Corona virus
Novel Corona virus
0 0
Azadi Ka Amrit Mahoutsav

InterServer Web Hosting and VPS
Read Time:1 Minute, 27 Second

Effectiveness of ChAdOx1 nCoV-19 (COVISHIELD) vaccine against the delta variant of SARS-CoV-2 in India

By PIB Delhi

SARS-CoV-2 has affected more than 200 million people causing more than 5 million deaths worldwide as per the WHO statistics. The rise in mutant variants of SARS-CoV-2 virus has led to concerns regarding vaccine effectiveness. Delta (B.1.617.2) variant is the predominant strain in India. The vaccination programme in India is driven largely by the Covishield vaccine (ChAdOx1 nCoV-19).

A multi-institutional team of Indian researchers led by Translational Health Science and Technology Institute (THSTI) evaluated the real-world vaccine effectiveness of Covishield during the SARS-CoV-2 infection surge between April and May, 2021, in India. They also assessed neutralising activity and cellular immune responses against the Variants in healthy vaccinated persons to understand the mechanisms of protection.

In the study published in journal “The Lancet Infectious Diseases” which included comparison between 2379 cases of confirmed SARS-CoV-2 infection and 1981 controls, the vaccine effectiveness against SARS-CoV-2 infection in fully vaccinated individuals was found to be 63%. The vaccine effectiveness of complete vaccination against moderate-to-severe disease was much higher at 81%. More importantly, the scientists also observed that the Spike-specific T-cell responses were conserved against both the delta variant and wild-type SARS-CoV-2. Such cellular immune protection might compensate for waning humoral immunity against the virus variants and prevent moderate-to-severe disease and need for hospitalisation. This study provides the comprehensive data on the real-world vaccine effectiveness and immunological response to vaccination which should help guide policy.

Publication Link: https://www.thelancet.com/action/showPdf?pii=S1473-3099%2821%2900680-0

About Post Author

Antara Tripathy

Chief Editor & CEO of IBG NEWS (09/Aug/2018-Present), Secretary of All Indian Reporter's Association,West Bengal State Committee. Earlier Vice President of IBG NEWS (01/Jan/ 2013-08/Aug/2018). She took over the charge from the Founder Editor of the Channel.
Happy
Happy
0 %
Sad
Sad
0 %
Excited
Excited
0 %
Sleepy
Sleepy
0 %
Angry
Angry
0 %
Surprise
Surprise
0 %

Advertisements

IBG NEWS Radio Services

Listen to IBG NEWS Radio Service today.


InterServer Web Hosting and VPS

Brilliantly

SAFE!

2022

LEAVE A REPLY

Please enter your comment!
Please enter your name here